Publications

Patents

Genetic regions & genes associated with increased yield in plants [patent]
WO2017106274A1

The present invention relates to methods and compositions for identifying, selecting and/or producing a plant or germplasm having root increased drought tolerance and/or increased yield under non-drought conditions as compared to a control plant. A maize plant, part thereof and/or germplasm, including any progeny and/or seeds derived from a maize plant or germplasm identified, selected and/or produced by any of the methods of the present invention is also provided.

Molecular markers asscociated with soy iron deficiency chlorosis [patent]
US9879326B1

The present invention relates to methods and compositions for identifying, selecting and/or producing a soybean plant or germplasm having iron deficiency chlorosis tolerance. A soybean plant, part thereof and/or germplasm, including any progeny and/or seeds derived from a soybean plant or germplasm identified, selected and/or produced by any of the methods of the present invention is also provided.

Genetic loci associated with increased fertility in maize [patent]
EP3107373A1

The present invention relates to methods and compositions for identifying, selecting and/or producing a maize plant or plant part having increased fertility. A maize plant or plant part that has been identified, selected and/or produced by any of the methods of the present invention is also provided.


Invited Seminars and Conference Presentations

2018

Joyn Bio, LLC Boston, MA
Genetics & Genome Editing for Sustainable Agriculture, by Elhan Ersoz

2017

Department of Crop Science, University of Illinois Urbana-Champaign IL
Genomics and Breeding: How to leverage genome editing for sustainable agriculture?, by Elhan Ersoz

2016

Dupont Pioneer Data Science Team, Johnston IA
Analysis of Large Data Collections for Predictive Inference: Path Analysis, SEM, Neural Networks and Tensors, by Elhan Ersoz


Dupont Pioneer Business Intelligence Team, Johnston IA
Cognition, Visualization and Augmented Intelligence in Agricultural Product Development, by Elhan Ersoz


Monsanto Emerging Leaders in Science- Data Science Focus Group, St. Louis MO
Computational Biology of Breeding: Translation of biological knowledge to product development for sustainable agriculture at the Age of Big Data , by Elhan Ersoz


Benson-Hill Biosystems, Computational Biology Team, StLouis MO
Genomics to Breeding: Implementation of Biological Knowledge for Product Development , by Elhan Ersoz


Preprints


Genetic analysis of lodging in diverse maize hybrids [preprint]
Larsson SJ, Peiffer, JA, Edwards, JW , Ersoz, ES, Flint-Garcia, S.A., Holland, J.B., McMullen, M.D., Tuinstra, M.R, Romay, C., Buckler, E.S.

Natural lodging due to severe weather conditions is a coomon occurance- with annual estimated yield losses of 5-20% . We have evaluated natural lodging that has occurred in a population of 1,723 diverse inbred maize genotypes that were crossed to a common tester and evaluated in five environments over multiple years. Several QTL identified in this study for lodging overlapped with loci previously mapped for stalk strength in related maize inbred lines. QTL intervals are enriched for candidate genes implicated in the regulation of lignin and cellulose synthesis.


Selected Publications

2018


Soil N2O emissions as affected by long-term residue removal and no-till practices in continuous corn. [publication]
Yuan M, Greer KD, Nafziger ED, Villamil MB, Pittelkow CM


Enhanced efficiency fertilizer impacts on yield-scaled nitrous oxide emissions in maize. [publication]
Graham R, Greer KD, MB Villamil, Nafziger ED, Pittelkow CM


Effects of pyraclostrobin foliar fungicide, corn hybrid, and harvest timing on stalk health of corn. [publication]
Shelby RJ, MB Villamil, KA Ames, CA Bradley


Exploring the relationships among greenhouse gas emissions, crop yields, and soil properties in cropping systems. [publication]
Behnke GD, CM Pittelkow, ED Nafziger, and MB Villamil


Carbon and nitrogen content of soil organic matter and microbial biomass under long-term crop rotation and tillage in Illinois, USA. [publication]
Zuber S, GD Behnke, ED Nafziger, and MB Villamil


Short corn rotations do not improve soil quality, compared to corn monocultures [publication]
Hoss M, GD Behnke, AS Davis, ED Nafziger, and MB Villamil


Long term crop rotation and tillage effects on greenhouse gas emissions, soil properties, and crop production in Illinois. [publication]
Behnke GD, SM Zuber, CM Pittelkow, ED Nafziger, and MB Villamil


A Modeling Framework to Evaluate the Impacts of Future Climate on Soil Organic Carbon Dynamics [publication]
Chu M, Guzman J, and MB Villamil


### 2014
The impact of population structure on genomic prediction in stratified populations [publication]
Guo, Z, Tucker, DM, Basten, CJ, Gandhi, H, Ersoz, E, Guo, B, Xu, Z, Wang, D, Gay, G

Population structure is an important factor that is often treated as a nuisance parameter in genetic mapping and genetic association studies- and is often acocunted for and discarded. In this study we show that depening on traits and species, population structure can explain a large fraction of heritable genetic variation for rice and maize, that can be leveraged to improve genetic prediction accuracies for phenotypes for genomic selection experiments when used in concert with other within sub-population genetic variance components.


### 2013
Accuracy of across-environment genome-wide prediction in maize nested association mapping populations [publication]
Guo, Z, Tucker, DM, Wang, D, Basten, CJ, Ersoz, E, Briggs, WH, Lu, J, Li, M Gay, G.

This study evaluated the accuracy improvements of across-environment predictions by using genetic and residual covariance across correlated environments as variables in a predictive model. Provided that sufficient marker density and significant correlation between environmnets are present, significant improvements in prediction accuracies can be achieved through inclusion of correlation between environments in the prediction model with little negative effects due to residual correlation.


#### 2012
SNP discovery with EST and NextGen Sequencing in Switchgrass (Panicum virgatum L.) [publication]
Ersoz, ES, Wright, MH , Pangilinan, JS, Sheehan, MJ, Tobias, C, Casler , MD, Buckler ES, Costich , DC

We generated and sequenced expressed sequence tag (EST) libraries from thirteen diverse switchgrass cultivars representing both upland and lowland ecotypes, as well as tetraploid and octoploid genomes. We followed this with reduced genomic library preparation and massively parallel sequencing of the same samples using the Illumina Genome Analyzer technology platform. EST libraries were used to generate unigene clusters and establish a gene-space reference sequence, thus providing a framework for assembly of the short sequence reads. SNPs were identified utilizing these scaffolds. We used a custom software program for alignment and SNP detection and identified over 149,000 SNPs across the 13 short-read sequencing libraries (SRSLs). Approximately 25,000 additional SNPs were identified from the entire EST collection available for the species. This sequencing effort generated data that are suitable for marker development and for estimation of population genetic parameters, such as nucleotide diversity and linkage disequilibrium.


#### 2011
Joint QTL Linkage Mapping for Multiple-Cross Mating Design Sharing One Common Parent [publication] Li, H; Bradbury, P; Ersoz, ES; Wang, J , Buckler, E.

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